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Chronic Lyme: Why It Often Requires a Functional Medicine Approach

Lyme and tick-borne co-infections rarely show up cleanly on standard testing. Here's how a functional medicine workup uncovers what's been missed.

June 20268 min readYour Health Now
Chronic Lyme disease and tick-borne illness assessment

Patients with chronic Lyme are often dismissed at the most frustrating moment of their journey - when the standard ELISA and Western blot come back negative, or when they're told their symptoms are 'just anxiety.' The truth is that conventional Lyme testing was designed for early, classic cases. It misses chronic, late-stage, and co-infected presentations regularly.

What chronic Lyme really looks like

  • Migrating joint pain, especially with no clear injury.
  • Severe, unrelenting fatigue that worsens with exertion.
  • Brain fog, word-finding trouble, and disrupted sleep.
  • Air-hunger, palpitations, or autonomic dysregulation.
  • Random, system-jumping symptoms that come and go in waves.

Better testing changes the picture

We use specialty labs that look for direct evidence (PCR), antibody patterns across more bands, and common co-infections - Babesia, Bartonella, Ehrlichia, and more. Just as importantly, we look at the inflammatory and immune fingerprint these infections leave behind, even when the bug itself is hard to detect.

When to suspect Lyme

If you have multiple symptoms across multiple body systems, if you've been worse since a flu-like illness or tick exposure (even years ago), or if you've seen several specialists with no clear answer - it's worth evaluating. Many of our patients didn't realize Lyme was on the table until five-plus years into their journey.

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